Word for inexplicable physical discomfort?

The particular sensation of physical discomfort upon viewing a lotus seed or lotus seed photo is called trypophobia. There is an interest group with 4000 members (1). Because photos of lotus seeds appear at the links, I include a couple of text extracts from them here:

The term trypophobia (sometimes called repetitive pattern phobia) was coined in 2005, a combination of the Greek trypo (punching, drilling or boring holes) and phobia. It is not recognized in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders. Thousands of people claim to be fearful of objects with small holes, such as beehives, ant holes, and lotus seed heads. Research is limited... – wikipedia

If you’re like me and you have a visceral reaction to the image above—if it makes your skin crawl, your hair hurt, and your stomach turn—you can count yourself among the trypophobic. According to its Facebook page, which is more than 4,000 members strong, trypophobia is fear of clustered holes. It is usually small holes in organic objects, such as lotus seed heads or bubbles in batter, that give trypophobics the extreme willies, triggering reactions like itchy skin, nausea and a general feeling of discomfort. – Popular Science