$E[e_te_s\Delta B_t\Delta B_s]$ for $\Delta B_t$ Brownian motion increments and $e_t(\omega)$ a measurable function.
Solution 1:
For every $i$, let $F_i=\sigma(B_s,s\leqslant t_i)$ then each $e_i$ is $F_i$-measurable and each $\Delta B_i$ is centered, independent of $F_i$, and $F_{i+1}$-measurable.
Now, fix $i\lt j$. Then $e_i$, $e_j$ and $\Delta B_i$ are all $F_j$-measurable and $\Delta B_j$ is independent of $F_j$ hence $e_ie_j\Delta B_i$ and $\Delta B_j$ are independent, a fact which implies $$E(e_ie_j\Delta B_i\Delta B_j)=E(e_ie_j\Delta B_i)\cdot E(\Delta B_j)=E(e_ie_j\Delta B_i)\cdot0=0.$$ Thus, the argument does not require to know the value of $E(e_ie_j\Delta B_i)$.
Likewise, for every $i$, $e_i$ is $F_i$-measurable and $\Delta B_i$ is independent of $F_i$ hence $$E((e_i\Delta B_i)^2)=E(e_i^2)\cdot E((\Delta B_i)^2)=E(e_i^2)\cdot(t_{i+1}-t_i).$$
Solution 2:
You can see it using the "tower property" for instance,
Assume $i<j$, then
$$E[e_i e_j \Delta B_i \Delta B_j] = E\left[ E[e_i e_j \Delta B_i \Delta B_j |\mathcal{F}_{t_j}]\right].$$
Now observe that since $i<j$ then $\mathcal{F}_{t_i}\subset \mathcal{F}_{t_j}$ and by hypothesis $e_i$ is $\mathcal{F}_{t_i}$-measurable and hence also $\mathcal{F}_{t_j}$-measurable, also $\Delta B_i = B_{t_{i+1}}-B_{t_i}$ is $\mathcal{F}_{t_j}$-measurable. Hence $$E[e_i e_j \Delta B_i \Delta B_j] = E\left[ e_i e_j \Delta B_i E[\Delta B_j |\mathcal{F}_{t_j}]\right].$$
Finally observe that $\Delta B_j$ is independent of $\mathcal{F}_{t_j}$ so $E[\Delta B_j |\mathcal{F}_{t_j}]=E[\Delta B_j]=0$ and hence
$$E[e_i e_j \Delta B_i \Delta B_j] = 0.$$
This was maybe very detailed but useful to understand why.