Is it possible to interact with animals in Fez?
Solution 1:
No, none where they talk or react back like the owls. If you run near the other perched birds, though, they'll fly away. And the turtles run toward you only to spin away when you come near.
1
Solution 2:
If you jump on some land creatures (Rabbits possibly?) they die and vanish; the turtles flash for a bit (mario tribute I believe).