Can I substitute the synonym "refuse" to check if a sentence with the word "disdain" makes sense?

I am trying to learn the meaning of the word disdain and how it is used in a sentence. It means to dislike of someone or something with the feeling that it does not deserve your respect or consideration. So if I am practicing sentence writing with the word disdain, can I substitute the word refuse to check if the sentence makes sense?

For example: The worker disdained the new tactics of dealing with customers.

To make sure the sentence makes sense, I substitute refuse: The worker refused the new tactics of dealing with customers.

Is it ok to substitute "refuse"?

Solution 1:

"The difference between the almost right word and the right word is really a large matter. It's the difference between the lightning bug and the lightning." (Mark Twain)

The connotations behind the two words in your usages could have a daylight of a difference between them.While there is nothing wrong with the sentences themselves (except that the full stop is conspicuously missing), the intended meaning could suffer for want of mot juste.