How do the aiming options work when in a vehicle in Grand Theft Auto V?

There is no autoaim while driving.

Aim and fire: no autoaim

  • R2 is drive
  • L1 is weapon aim (white dot)
  • right stick steers weapon
  • R1 shoots weapon
  • left stick steers car

Just Fire (same as PS3):no autoaim.

L1 is both aim and shoot.