Soft or more euphemistic way of saying "suffer"
Solution 1:
Struggle with
Agonise over
Contend with
Deal with
Trouble over
Solution 2:
I particularly like deal with, proposed by @MDMcDMD. Here's a way to use it:
My mother-in-law has her arthritis to deal with.
Alternatively:
We all have our troubles
is a nice way of complaining.
Here's a nice made-up noun my German spouse invented once:
... the tougheties of life
Solution 3:
How about overcome challenges?