Remove all spaces and tabs from ONLY specified segment line?

I use Notepad++ v8.1.1.

How to find a specific segment and remove all spaces and tabs from ONLY that segment?

E.g. I want to find all "EQD" lines and remove all spaces and tabs from JUST those lines.

Sample data:

EQD+CN+ZMLU XXXXXXX+45GP+++5  
NAD+CA+ZMLU:172:ZZZ  
LOC+147+0260808::5  
FTX+AAA+++ALUMINUM ARTICLES  
MEA+WT++KGM:16549  
LOC+9+DOHAI:139:6  
LOC+11+USSAV:139:6  
RFF+BM:1  
EQD+CN+ZMLU XXXXXXX+45GP+++5  
NAD+CA+ZMLU:172:ZZZ  
LOC+147+0260202::5  
FTX+AAA+++ALCOHOLIC BEVERAGES  
MEA+WT++KGM:27797  
LOC+9+JMKIN:139:6  
LOC+11+USSAV:139:6  
RFF+BM:1  
EQD+CN+ZMLUXXXXXXX+45GP+++5  
NAD+CA+ZMLU:172:ZZZ  

If "EQD" only appears at the beginning of line, the following would work:

Find what: (^EQD\S*)(($)|(\s))
Replace with: $1$3

If you have more than one space/tab per line, you will need to click on Replace All several times.