Host wildcard subdomains using postfix

I'm trying to work out how I can get postfix to accept email for any sub-domain of my main site. I don't have virtual domains, just a long list of sub-domains for local delivery. In specific, I'm feeding python@*.mydomain.com into a Python using the alias file:

python:    |/www/proc_email.py

The Python can handle delivery from there. I envision this looking something along the lines of:

mydestination = encendio, localhost.localdomain, localhost, *.mydomain.com

I'm running the latest version of postfix on Ubuntu (not rightly sure how to check the version).

Thanks in advance.

You can't use wildcards if you explicitly list the destinations in your Postfix config, but fortunately the $mydestination option accepts table lookups. So try setting $mydestination to a pcre map like this:

mydestination = pcre:/etc/postfix/mydestinations

Then create /etc/postfix/mydestinations with properly anchored and escaped regexps:

/^encendio$/                  ACCEPT
/^localhost\.localdomain$/    ACCEPT
/^localhost$/                 ACCEPT
/^.*\.mydomain\.example$/     ACCEPT

Technically you could put anything at all in the place of "ACCEPT" as the result is ignored; just the presence of the match is sufficient:

Specify a list of host or domain names, "/file/name" or "type:table" patterns, separated by commas and/or whitespace. A "/file/name" pattern is replaced by its contents; a "type:table" lookup table is matched when a name matches a lookup key (the lookup result is ignored).

The pcre solution in the accepted answer works well, but you might want to consider anchoring the regexp to avoid getting hits on just part of the domain name.

/^encendio$/                  ACCEPT
/^localhost\.localdomain$/    ACCEPT
/^localhost$/                 ACCEPT
/^.*\.mydomain\.com$/         ACCEPT

*.mydomain.com wont work.

You need to create relay-domains and put all your subdomains in there. 1 per line.