CSS transition shorthand with multiple properties?

Syntax:

transition: <property> || <duration> || <timing-function> || <delay> [, ...];

Note that the duration must come before the delay, if the latter is specified.

Individual transitions combined in shorthand declarations:

-webkit-transition: height 0.3s ease-out, opacity 0.3s ease 0.5s;
-moz-transition: height 0.3s ease-out, opacity 0.3s ease 0.5s;
-o-transition: height 0.3s ease-out, opacity 0.3s ease 0.5s;
transition: height 0.3s ease-out, opacity 0.3s ease 0.5s;

Or just transition them all:

-webkit-transition: all 0.3s ease-out;
-moz-transition: all 0.3s ease-out;
-o-transition: all 0.3s ease-out;
transition: all 0.3s ease-out;

Here is a straightforward example. Here is another one with the delay property.

Edit: previously listed here were the compatibilities and known issues regarding transition. Removed for readability.

Bottom-line: just use it. The nature of this property is non-breaking for all applications and compatibility is now well above 94% globally.

If you still want to be sure, refer to http://caniuse.com/css-transitions

If you have several specific properties that you want to transition in the same way (because you also have some properties you specifically don't want to transition, say opacity), another option is to do something like this (prefixes omitted for brevity):

.myclass {
    transition: all 200ms ease;
    transition-property: box-shadow, height, width, background, font-size;
}

The second declaration overrides the all in the shorthand declaration above it and makes for (occasionally) more concise code.

/* prefixes omitted for brevity */
.box {
    height: 100px;
    width: 100px;
    background: red;
    box-shadow: red 0 0 5px 1px;
    transition: all 500ms ease;
    /*note: not transitioning width */
    transition-property: height, background, box-shadow;
}

.box:hover {
  height: 50px;
  width: 50px;
  box-shadow: blue 0 0 10px 3px;
  background: blue;
}

<p>Hover box for demo</p>
<div class="box"></div>

Demo