Disable the auto-upload that occurs on each save

Solution 1:

Look for the OneDrive icon in the System Tray (bottom RH corner of the screen). Right click and select Settings. On the Settings, goto office Tab and uncheck "Use Office to sync office files". Reboot. Cross fingers.

You will get your life back.

Solution 2:

Okay, here's an idea.

Delete the following file:

C:\Program Files\Microsoft Office\Office15\MSOSYNC.exe

Source: http://www.technotrickies.com/2014/10/how-to-disable-auto-start-of-microsoft.html

Edit: Apparently, new location of MSOSYNC is C:\Program Files\Microsoft Office\root\Office16 (thanks to @feetwet)

Solution 3:

Possibly this:

Right-click the SkyDrive icon in the notification area, at the far right of the taskbar. (You might need to click Show hidden icons first to see the icon.) Then click Settings. On the Settings tab, under General, deselect Use Office to sync files faster and work on files with other people at the same time, and then click OK.

Credit to geek-o-matic

http://answers.microsoft.com/en-us/office/forum/office_2013_release-office_storage/how-to-disable-microsoft-upload-center-2013/8bbc93e6-bc3b-4414-a1d3-9f37c3ed2d6e