How to bypass "This app has been blocked for your protection" error
Solution 1:
This solution require you be logged in as an Administrator user. If you are on a domain and not an Administrator on the domain itself this won't work. Once you are done running this program you should re-enable Windows SmartScreen.
You need to locate System and Security within Control Panel. How you access this is slightly different on certain builds of Windows 10. The following screenshot is from a build that used the traditional Control Panel and only used as guidance.
Once you have located the System and Security section of the Control Panel you need to click on Action Center. You can also gain access to this window by right click on the flag icon in your taskbar if it is there.
Once you have Action Center locate the Windows SmartScreen option and disable it. You will be given a UAC prompt which you will have to approve.
Once you have confirmed the program is able to run, and you are done with your task, enable the Windows SmartScreen feature again.
Source
Solution 2:
==SOLUTION==
Click Start, type cmd and run with admin privileges. Then input your desired program path:
C:\Users\my_user\Desktop\program.exe
p.s. note to 'downvote brigade': it's better you allowed other people to get help from this post, instead of clicking "delete & downvote".
Solution 3:
There is usually a Ignore this warning
or similar text in the bottom right hand corner of the dialogue. The thing that makes this text hard to see is that it has a very similar color to the Windows theme color. Clicking that link will temporarily turn off Windows SmartScreen