Alternative Large Cursors and show tooltips

Solution 1:

You can make custom cursors with a graphics program and apply them using Pinpoint. Here's the relevant video on how it's done.

Solution 2:

I think Mouseposé or PinPoint will help you out by providing a highlight around a normal size cursor that isn't opaque like the normal cursor so you can still read the tooltips. They're not free, but it may be your only option.