Storage of User Profile Disks on file server cluster (SOFS or normal)

Solution 1:

SOFS isn't expected to work with anything except supported scenarios: Hyper-V VMs, and SQL Server databases. Reason is simple: SOFS uses CA (Continuously Available) File Shares and these "guys" aren't cached, so "general purpose" file access performance is going to be mediocre at best.

https://blogs.technet.microsoft.com/clausjor/2012/06/07/smb-transparent-failover-making-file-shares-continuously-available/

https://technet.microsoft.com/en-us/library/hh831349(v=ws.11).aspx