MacOS app does not run on the Xcode simulator
Solution 1:
I had a similar problem with Xcode 4.5.2.
To fix it I had to go to the menu Product > Edit Scheme... > Select "Run " (in the sidebar) > Info (tab). In here is a drop down box labeled Executable, select it and choose your app that you wish to launch when the Run button is clicked.
Solution 2:
I messed up my settings and had this same issue - builds the app but doesn't launch (either in the simulator or the device).
The answer Product > Edit Scheme got me half way there - then choose Run {your app} on the left. There is a launch Automatically radio button to check: