With autorun on, how can I ensure click-to-move kicks in when I click on an object or NPC?

Solution 1:

I just tested this out, and with Click to Move on I still can't bind the right mouse button (used for Click to Move) to autorun.

I suspect you had two different settings - Click to Move which works as you described, and Toggle Autorun under Key Bindings, in the Movement Keys section, bound to something else (maybe Middle Mouse, which is bindable).

Solution 2:

It may be as simple as enabling "click to move" under mouse settings in interface. By default, that command is off. I can still do it. I have toggle autorun on one of my side buttons, and right click turns it off and sends me over to wherever I clicked.