Chrome DOM breakpoint keeps enabling itself

solution here: http://code.google.com/p/chromium/issues/detail?id=91666

To purge all breakpoints open inspector on inspector (undock first inspector and hit ctrl-shift-I to open the second) and run "WebInspector.settings.domBreakpoints.set([])" in second inspector's console.

2021 Edit: This answer is now a decade old, there are multiple alternatives in the comments to this answer. I haven't tested them, the most up to date is from @reuben-thompson: window.localStorage.clear()

Sometimes when you set breakpoints you also autoenable "pause on exceptions". This will give unwanted persistant breakpointy behaviour. Cycle through the "pause on exceptions" button (bottom left) in order to switch it off (note- it is not on/off but three possible states)