What is the game-time to real-time ratio in Fallout: New Vegas?

Solution 1:

One in-game-hour transpires in two real time minutes. This can be adjusted by changing the Timescale variable using the console, but I would not recommend it.

Keep in mind that, for objectives like the ones you describe, if you miss them, you can always wait 22 hours (or whatever) and try again. Just be mindful of your Hunger/Thirst/Exhaustion meters if you're playing on Hardcore.