Can I create a virtual 3d model of a building from 2 dimensional blueprints on PDF?

This is not an easily automated task. Depending on what you want to do with this model or what your motivation for learning how to do it is, you might be better off just finding someone who has 3D modeling experience and asking them to model it for you. If there is a local college or university near you that has an architecture program you might be able to find a student to do this for you relatively inexpensively.

Sketchup is a pretty accessible program to start with if you want to do it yourself and end up with a model file, but it's pretty basic as far as architectural modeling tools go (which is good if you want to start learning how to model, but not so good if you want a robust model). Autodesk has a free online tool called HomeStyler that might suit your needs, again depending on what you want to use the model for since it might not be possible to export a model, just work with it online.