How to fix skipping/stuttering audio in Google Chrome
I was able to resolve this issue by disabling the "pepper" Flash player and installing the latest full version of Flash.
To do this, go to chrome://plugins/ in the Chrome browser and disable the Flash plugin that's there (the location will be something like C:\Program Files\Google\Chrome\Application\23.0.1271.64\PepperFlash\pepflashplayer.dll).
Once it's disabled you can go to youtube.com (or some other Flash-dependent website) and follow the hyperlinks provided to get the latest version of Flash (or just go directly to the Adobe Flash website and get it there).