Can I use two series of commas in the same phrase or sentence?

Example phrase: Which one may be correct?

rich, strong, and fast man, white woman, boy, and girl

Coordinating four nouns "man, woman, boy, and girl" whatever the places of modifiers.

rich, strong, and fast man and white woman, boy, and girl**

The conjunction "and" is coordinating two noun phrases whatever the places of modifiers.

There is an option of using semi-colons as higher-level separators but I wouldn't bother with anything as simple as your first example. I might for something like:

rich, ugly, old man; thin, young, white woman; and pretty, poor girl.

There was a rich, ugly, old man, a thin, young, white woman, and a pretty, poor girl.