Debugging in Safari's Web Inspector, when using a module loader like SystemJS

Well, maybe you can use some IDE like WebStorm with a strong Debugger for Web and Node.

Examples:

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You can see more about WebStorm debugger here.

Some alternatives for WebStorm:

  1. Atom (Free)
  2. Intellij IDEA (community: Free)
  3. Visual Studio Code (Free)
  4. ...

P.S: I develop Ionic and React apps with WebStorm :D