Does smoothness of left and right multiplication imply smoothness of multiplication?
Solution 1:
It is proven in
Ellis, Robert, Locally compact transformation groups, Duke Math. J. 24, 119-125 (1957). ZBL0079.16602.
that a locally compact Hausdorff topological space equipped with a group structure where both left and right multiplications are continuous, is actually a topological group, i.e. the multiplication is jointly continuous. Now, you can use the result that a topological manifold which is also a topological group admits a unique Lie group structure.