macOS suddenly exhibits weird mouse acceleration after idling

I've had similar issues with a Logitech MX2 & Logi Options.
My bet is the Logi controller that 'forgets' what it's doing.

Tests would include:-

  • uninstalling their drivers & see if the same happens without;
  • test a different mouse;
  • see if your G-series can be used fully with something like SteerMouse or USB Overdrive.