Do enemies in Void Bastards respawn? Can I make it stop?
From the Fandom wiki :
Biological enemies can spawn infinitely from various rifts throughout the ships, but mechanical enemies like Secbots and Turrets only appear in limited quantities per ship and do not respawn. Certain enemies like Tydybots and Pirates will only appear on a ship under specific circumstances.
Rifts looks like this :
Sealing the doors of the room where the rift is seems the only way to deal with it.