Does poison resist matter for Speaking with Silence?

In Skyrim, when working on the Speaking with Silence quest for the Thieves' Guild, you end up sedated by a poisoned arrow while Mercer and Karliah discuss the good old times.

Considering vampires have a 100% resistance to poison, would being a vampire in that situation make any difference?

Solution 1:

No it would not,game uses "trigger" to sedate you.It works on engine basis not gameplay basis.

There is just too much things that can go wrong if they equipped someone with 1st poison arrow and left it to attack first enemy,what if someone gets there and conjures creature to be hit by an arrow first?

Not to mention the character specifications as items,levels,bonuses,resists...