Word with a meaning of "personal internal struggle"

A word for a thing that someone can mentally struggle with, or has a quirk for, kind of like (but not) hubris.

I've seen it around, but only a few times, and I can't for the life of me think what it was! I think it had something to do with neuro? Not neurotic, though.

As in 'Alexis struggled with many (word)'.

Neuroses was the word I was looking for, thank you @stevesliva !

Perhaps you are looking for neuroses, from the singular neurosis. A plain English synonym being might be hangups.

neurosis - (in non-technical use) excessive and irrational anxiety or obsession

hang-up - An emotional problem or inhibition

(Oxford Dictionaries)