Remove multiple items from a Python list in just one statement

In Python, creating a new object is often better than modifying an existing one:

item_list = ['item', 5, 'foo', 3.14, True]
item_list = [e for e in item_list if e not in ('item', 5)]

Which is equivalent to:

item_list = ['item', 5, 'foo', 3.14, True]
new_list = []
for e in item_list:
    if e not in ('item', 5):
        new_list.append(e)
item_list = new_list

In case of a big list of filtered out values (here, ('item', 5) is a small set of elements), using a set is faster as the in operation is O(1) time complexity on average. It's also a good idea to build the iterable you're removing first, so that you're not creating it on every iteration of the list comprehension:

unwanted = {'item', 5}
item_list = [e for e in item_list if e not in unwanted]

A bloom filter is also a good solution if memory is not cheap.

You can do it in one line by converting your lists to sets and using set.difference:

item_list = ['item', 5, 'foo', 3.14, True]
list_to_remove = ['item', 5, 'foo']

final_list = list(set(item_list) - set(list_to_remove))

Would give you the following output:

final_list = [3.14, True]

Note: this will remove duplicates in your input list and the elements in the output can be in any order (because sets don't preserve order). It also requires all elements in both of your lists to be hashable.

You can use filterfalse function from itertools module

Example

import random
from itertools import filterfalse

random.seed(42)

data = [random.randrange(5) for _ in range(10)]
clean = [*filterfalse(lambda i: i == 0, data)]
print(f"Remove 0s\n{data=}\n{clean=}\n")


clean = [*filterfalse(lambda i: i in (0, 1), data)]
print(f"Remove 0s and 1s\n{data=}\n{clean=}")

Output:

Remove 0s
data=[0, 0, 2, 1, 1, 1, 0, 4, 0, 4]
clean=[2, 1, 1, 1, 4, 4]

Remove 0s and 1s
data=[0, 0, 2, 1, 1, 1, 0, 4, 0, 4]
clean=[2, 4, 4]

I'm reposting my answer from here because I saw it also fits in here. It allows removing multiple values or removing only duplicates of these values and returns either a new list or modifies the given list in place.

def removed(items, original_list, only_duplicates=False, inplace=False):
    """By default removes given items from original_list and returns
    a new list. Optionally only removes duplicates of `items` or modifies
    given list in place.
    """
    if not hasattr(items, '__iter__') or isinstance(items, str):
        items = [items]

    if only_duplicates:
        result = []
        for item in original_list:
            if item not in items or item not in result:
                result.append(item)
    else:
        result = [item for item in original_list if item not in items]

    if inplace:
        original_list[:] = result
    else:
        return result

Docstring extension:

"""
Examples:
---------

    >>>li1 = [1, 2, 3, 4, 4, 5, 5]
    >>>removed(4, li1)
       [1, 2, 3, 5, 5]
    >>>removed((4,5), li1)
       [1, 2, 3]
    >>>removed((4,5), li1, only_duplicates=True)
       [1, 2, 3, 4, 5]

    # remove all duplicates by passing original_list also to `items`.:
    >>>removed(li1, li1, only_duplicates=True)
      [1, 2, 3, 4, 5]

    # inplace:
    >>>removed((4,5), li1, only_duplicates=True, inplace=True)
    >>>li1
        [1, 2, 3, 4, 5]

    >>>li2 =['abc', 'def', 'def', 'ghi', 'ghi']
    >>>removed(('def', 'ghi'), li2, only_duplicates=True, inplace=True)
    >>>li2
        ['abc', 'def', 'ghi']
"""

You should be clear about what you really want to do, modify an existing list, or make a new list with the specific items missing. It's important to make that distinction in case you have a second reference pointing to the existing list. If you have, for example...

li1 = [1, 2, 3, 4, 4, 5, 5]
li2 = li1
# then rebind li1 to the new list without the value 4
li1 = removed(4, li1)
# you end up with two separate lists where li2 is still pointing to the 
# original
li2
# [1, 2, 3, 4, 4, 5, 5]
li1
# [1, 2, 3, 5, 5]

This may or may not be the behaviour you want.

I don't know why everyone forgot to mention the amazing capability of sets in python. You can simply cast your list into a set and then remove whatever you want to remove in a simple expression like so:

>>> item_list = ['item', 5, 'foo', 3.14, True]
>>> item_list = set(item_list) - {'item', 5}
>>> item_list
{True, 3.14, 'foo'}
>>> # you can cast it again in a list-from like so
>>> item_list = list(item_list)
>>> item_list
[True, 3.14, 'foo']