Does Assassin's Creed: Brotherhood build on the saved game from Assassin's Creed II?
Some games (like Mass Effect 2) build on the saved games from earlier versions by allowing the player to keep going with the choices they'd made earlier. Assassin's Creed isn't big on non-linearity, but my ACII character does have nice armor, weapons, and some cash.
Will AC: Brotherhood notice that saved game and pick up information from it or does Brotherhood always start from scratch?
Solution 1:
No it will not.
Assassins Creed Brotherhood will always play exactly the same way regardless of whether you have an Assassins Creed II save game.