The simpsons hit and run for pc takes too long to load?

Set compatibility mode for Windows 98 like 123iamking's answer is an easy & simple way. But each time you run the game, it requires Administrator right.

So here is a way you can run the game without Administrator right: set affinity to 1 core with cmd.

Step 1: Create a bat file called Simpsons.bat in the game directory.

In the file Simpsons.bat, use affinity cmd:

start /affinity 1 Simpsons.exe

Step 2: Edit the game shortcut so that it run Simpsons.bat instead of Simpsons.exe

Just run the game in compatibility mode for Windows 98

Thanks to Sargon for recommend this in a Youtube comment

I recommend just running it in Windows 98 compatibility mode. It will automatically set affinity to 1 core and you won't have to do it manually every single time. Sure it's just 1 core, not 2, but this is such an old game that it won't matter.