Creating aliases for iTerm 2 that work during ssh

If you use oh-my-zsh, you will want to place those in ~/.zshrc

vi ~/.zshrc

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# Example aliases
# alias zshconfig="mate ~/.zshrc"
# alias ohmyzsh="mate ~/.oh-my-zsh"
alias work="cd ~/Lucas/local-sites/"

Have you tried creating a .bashrc file with these aliases?

It should be created in your home folder ~/.bashrc