Is it correct to use "most" + "-est" together?

No it is not ok to use more + -er or most + -est, unless you want to sound childish.

Cambridge:

Warning:
We do not use more or most together with an -er or -est ending:

They emigrate because they are looking for a better life.
Not: … a more better life

The beach at Marmaris is one of the biggest in Turkey.
Not: … the most biggest


Not "OK". If you want to go "over the top", then it should not be with a grammatical error but rather using extra (or arguably extraneous) adjective(s):

Welcome to the absolutely, positively wildest show on earth.