Does Pokémon GO have any interoperability with handheld Pokémon games?

Is there any form of cross-play supported between Pokémon GO and the handheld Pokémon RPGs such as X, Y, Omega Ruby, or Alpha Sapphire?

Solution 1:

As far as I'm concerned, there are no plans for the future of cross-play, at least not something they announced.

There are, on the other hand, some declarations that were made from Nintendo that "they would like to add cross-play with Pokémon Sun & Pokémon Moon" but I assume they will decide to do it or not depending on the amount of people playing when the summer is over.

If I find the original interview where they said it, I will edit the answer to add some links.

EDIT: It seems that the team responsible for this project said in the E3 that they had the plans to tie-in both the new gen games and Pokémon GO:

"While explaining the uses of the GO+, the team also revealed that Pokemon GO and the GO+ will eventually tie-in to Pokemon Sun and Pokemon Moon. There was no explanation about how this will work at this point in time."

I still think that it will depend on the player base at the end of the summer, but we will see eventually.

http://gamerant.com/pokemon-go-release-window-sun-moon-e3/

Solution 2:

There have been no announcements even hinting at this as a possibility, but other factors make this seem highly unlikely.

• The underlying mechanics regarding stats and possible moves are completely different and would be difficult to translate from PoGo to the main series or vice versa.

• Pokemon Go is made by a different company than the main series installments.