Similar phrases/words meaning "it is worth mentioning"

What could be the other phrases/words with similar meaning of "it is worth mentioning"? e.g. I would like to start a sentence with exactly same meaning of

It is worth mentioning that [......]

Practically anything you put here might have "exactly the same meaning as" It is worth mentioning that, because the original phrase has so little meaning in the first place. If it has an actual meaning, it has very little to do with the literal meaning; it's more a hedge, apologizing for adding something which has only a tenuous connection with your main argument. You could try these:

It may perhaps be observed without straying too far afield from our primary focus that . . .

It is although distant from our current discourse not altogether irrelevant to adduce here the fact that . . .

In light of what was written in 3.2.4 above anent the apparent inconsistency between my current position and that articulated in Sartorius (1937), I may perhaps be forgiven for calling attention here to the fact that . . .

But by and large it may be taken for granted that if you mention a fact you consider it worth mentioning. You provide your reader no new information by laboring the point; you will do better to restrict yourself to a simple Note that or Observe that—or, even better, state frankly why the point is worth mentioning.

As a side note, ...

Another aspect of this is ...

Secondary to [such and so] is [this other thing].

There's an additional aspect of this:

There's more:

A related point to consider is ...

For the ultra-aspirational:

"It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material."

A good word for this is apropos--a loanword from French. It literally translates as "to the purpose." Apropos of your question, you could also preface your sentence with incidentally, but I digress.