How to create desktop shortcut for Chrome profile and run two or more profiles simultaneously?

Since there are several possible answers, I will introduce a more exotic one:

• Download and install Platypus

• Create a file chromedefault.sh in ~/Documents/scripts/ with the content:

  #!/bin/bash
  open -a "Google Chrome" --args --profile-directory=Default
  

• Open Platypus with the following settings:

  

  and create a new "app" ChromeDefault.

• For a second app with the profile Other use another script chromeother.sh with appropriate changes:

  #!/bin/bash
  open -a "Google Chrome" --args --profile-directory=Other
  

  and call it ChromeOther.

• Put both apps in the /Applications folder and create as many symlinks or aliases as needed.

Open Script Editor from /Application/Utilities >> create a new doc >> paste following:

do shell script "/Applications/Google\\ Chrome.app/Contents/MacOS/Google\\ Chrome --profile-directory=Profile\\ 3 > /dev/null 2>&1 &"

FYI:

\\ contains a space (the first back slash escapes the second back slash which escapes the space!);

and user profile ../Chrome/Profile 3 will be --profile-directory=Profile\\ 3 in the code, ../Chrome/Profile 2 will be --profile-directory=Profile\\ 2, ../Chrome/Default will be --profile-directory=Default

Try to run it and save it if it works.