Is there a word for something someone is known for?
Signature is the answer. Both as a count noun and an adjective.
[count noun] something (such as a quality or feature) that is closely associated with someone or something — usually singular
Her latest movie includes the humor and fast pace that have become her signature.
[adjective] closely associated with someone or something : making a person or thing easy to recognize
the chef's signature dish
“Respect” is her signature song/tune.
The director's new movie is a return to his signature style.http://www.learnersdictionary.com/definition/signature
Trademark: A distinctive characteristic by which a person or thing comes to be known.
E.g. (Lifted from @ermanen)...
...1-Her latest movie includes the humor and fast pace that have become her trademark.
2-The shuffle and snicker that became the comedian's trademark.
*Though "signature" would be the first thought for something that someone is particularly known for.*