Getting list of lists into pandas DataFrame

Call the pd.DataFrame constructor directly:

df = pd.DataFrame(table, columns=headers)
df

   Heading1  Heading2
0         1         2
1         3         4

With approach explained by EdChum above, the values in the list are shown as rows. To show the values of lists as columns in DataFrame instead, simply use transpose() as following:

table = [[1 , 2], [3, 4]]
df = pd.DataFrame(table)
df = df.transpose()
df.columns = ['Heading1', 'Heading2']

The output then is:

      Heading1  Heading2
0         1        3
1         2        4

Even without pop the list we can do with set_index

pd.DataFrame(table).T.set_index(0).T
Out[11]: 
0 Heading1 Heading2
1        1        2
2        3        4

Update from_records

table = [['Heading1', 'Heading2'], [1 , 2], [3, 4]]

pd.DataFrame.from_records(table[1:],columns=table[0])
Out[58]: 
   Heading1  Heading2
0         1         2
1         3         4