key presses repeat or not register at all, is it Windows or Mobo
Boot with a bootable USB Key. Any OS and an editor or something to type into.
You may need to temporarily disable Secure Boot.
Type for a while and see if the problem occurs this way.
If yes, then the motherboard is suspect.
If no, then Windows will need a Repair Install using the Microsoft Media Creation Link.
https://www.microsoft.com/en-us/software-download/windows10
You replaced the motherboard, so it seems most likely Windows needs to be repaired. Use the Windows 10 Repair Install as I noted and use the option to Keep Everything as the first option to try.