Solution 1:

My own solution to the problem of lag with wireless mouse, is not to use one.

If you want your mouse to be responsive under conditions of heavy use, use a USB mouse.

I just remark that a PS2 mouse is even more responsive, but very few computers today have the outlet.

(The above reflects my personal experience, and might not be valid for all computer/mouse/driver combinations.)

Solution 2:

My solution was to buy a USB extender cable so the transmitter is placed further away from the PC case.

When there was a lot of activity on my HDDs, the mouse started lagging/stuttering. Anyone with this problem should give it a try. Could be your PC components interfering with the wireless USB mouse.

Solution 3:

moving the USB wireless dongle from the back of my PC to the USB hub I have at the other end of my desk worked for me.