Will TPM and Secure boot complicate hardware upgrades and changes? [closed]

Will changes like GPU, RAM, HDDs or OS transfer render boot failures or forcing a clean install?

If your system does not meet the requirements for Windows 11 when it's released later this year then you will be unable to upgrade to Windows 11. If you install a Windows 11 Insider Preview build, despite your system not meeting the requirements, you will eventually be required to perform a clean install back to Windows 10.

Once Windows 11 is generally available, these PCs will be opted out of flighting and will not be able to receive future Windows 11 Insider Preview builds. These PCs must clean install back to Windows 10 with the media (ISOs) that we provide and can then join the Release Preview Channel to preview Windows 10 updates.

The requirements for TPM 2.0 and WDDM 2.x are built into the setup of Windows 11. Secure Boot has been supported for nearly 14 years. Microsoft is still making a final determination of what the minimum system requirements will be for Windows 11.

Will it deny the use of any obscure hardware?

Windows has never required a clean install if you replaced the GPU, RAM, and/or HDD in a system. You can clone your HDD to a SSD all day long, and Windows will never have a problem being activated, on the same system. Windows since Windows 7 has only really only cared about the motherboard when it came to activation of the installation. Windows 10 was primarily a digital entitlement. Secure Boot support has been a requirement on ALL OEM devices since Windows 8.1. UEFI has been supported since Windows 7 (although a 32-bit UEFI kernel could invalidate some device).

There is obviously zero upgrade path to Windows 11 without a clean install if you are running a 32-bit version of Windows 10. Since Microsoft has not indicated if they will offer Windows 11 for free to anyone other than Windows 10 users, the same statement applies to 32-bit Windows 7 and Windows 8.x installation, a clean install to Windows 11 would be required if a free upgrade was offered.

The requirements for the first Insider Preview build of Windows 11 will be significantly different then the RTM build of Windows 11 later this year. If your machine can run Windows 10 today, it will for a time until Windows 11 is released, be able to run the Insider Preview builds for Windows 11 until it's actually released. It does appear the Insider Preview builds to Windows 11 will require a clean install if your system does not meet the requirements.

What is clear, if your device does not support UEFI, it will not run Windows 11. UEFI has been around for more than 20 years.

Source: Preparing for Insider Preview Builds of Windows 11