How can I fix stuttering and lag issues in Deus Ex HR Director's Cut?

Assuming you have a NVidia graphics card (which is what normally causes this problem) you can make the following registry change to resolve this issue:

Open the Windows registry editor:

• Open the Start Menu
• Type in regedit.exe

For the original release:

• Go to HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HR

For the Director's Cut:

• Go to HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HRDC for Director's Cut

Change this value to 1 to disable graphics optimisations:

• Set D3D11_CREATE_DEVICE_PREVENT_INTERNAL_TH­READING_OPTIMIZATIONS to 1

Alternatively, if the above doesn't resolve the issue for you, you can also try setting the following values as well - this should work regardless of graphics card vendor;

• In HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HRDC, locate AllowJobStealing and set it to 0

Finally, specifically for owners of NVidia graphics cards;

• In HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HRDC\Graphics, locate AtiForceFetch4 and set it to 0

For the original release of Deus Ex: Human Revolution, change the above registry keys from HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HRDC to HKEY_CURRENT_USER\Software\Eidos\Deus Ex: HR.

A couple more solutions from around the internet, which I'll offer up. They didn't work for me but apparently they work for some people.

1. Run Google Chrome in background
2. Use the app from http://www.lucashale.com/timer-resolution/ and set it to the highest setting, it changes the timer
3. Change from fullscreen to windowed, and then alt-tab back to the game again so it'll go fullscreen
4. Turn off triple buffering

Love to see some more suggestions.