Changing screenshot directory in Ubuntu 21.10

Solution 1:

if using Screenshot Tool from the drop down menu in the Taskbar select Settings then the Storage tab.

The Save Location can be changed there.

Solution 2:

I found the solution and it was within the set I had put above. However, it has a little twist that was missing from the answer provided here.

It is possible to use the Screenshot location extension but instead of looking for the Extensions tab within Tweaks, just go directly to the Gnome Installed Extensions page and then click on the configuration button for the Screenshot location extension and select the folder you want and voilà.

Here is a screenshot of the configuration window: