In Framing Frame, will the guards get alerted if they see a missing painting?

In this heist, it's possible to steal the paintings without killing all the guards. But if one of them see any missing painting, will he trigger the alarm ?

No, the guards will not get alerted from a missing painting.

While the guards will not be alerted if they don't see the painting where it belongs.

I highly recommend to be careful when moving the paintings because the cameras can be alerted to them.

Guards will be alerted if they see the painting on the floor.

Example: One time I threw a painting in the camera's range and it alerted everyone.

Mission Items in general are never detected to be missing when you take them otherwise day 3 for framing frames would require you to take out all the guards first.