"What can I be of help"
Solution 1:
The sentences contains some quirks, and a lot of references are omitted.
Sense is not quantifiable, so the variation a lot of sense feels more natural and is more commonly used than lots of sense.
The expression isn't what can I be of help but rather what I can do to help or how I can be of help.
I fleshed out the sentences so that they read like written language:
That makes a lot of sense. I'm not sure what I can do to be of help (and I already have two sessions on the official schedule), but I would be happy to be of help.
Solution 2:
Better to say How can I be of help? or What can I help with? (yes I know there is a preposition at the end), or even more simply How can I help?