Shortcut to jump to last non-empty row in range skipping empty rows
Solution 1:
As mentioned above in comments, CTRL+END will take you to the last cell in the worksheet.
If you want to go to the last cell in a column, AFAIK, you may need a macro as (which you noticed) CTRL+DOWN will stop at the first empty cell.
Put this macro in a module in your workbook, and you can then assign a keyboard shortcut to it and it'll select the last non-empty cell in the active column.
Sub gotoLastRow()
With ActiveSheet
.Cells(.Rows.Count, ActiveCell.Column).End(xlUp).Select
End With
End Sub