AMDGPU-Pro drivers fail to install on Ubuntu 16.04, how to fix it?

Solution 1:

Try adding the i386 architecture:

sudo dpkg --add-architecture i386

Then try the setup again.

Solution 2:

For me, this helped:

If you experience issues [5] with a AMD R9 390 series graphics card, set radeon.cik_support=0 radeon.si_support=0 amdgpu.cik_support=1 amdgpu.si_support=1 amdgpu.dpm=1 amdgpu.dc=1 as kernel parameters to force the use of amdgpu driver instead of radeon.

If it still does not work, try disabling DPM, by setting the kernel parameters to: radeon.cik_support=0 radeon.si_support=0 amdgpu.cik_support=1 amdgpu.si_support=1

Source: https://wiki.archlinux.org/index.php/AMDGPU#R9_390_series_poor_performance_and/or_instability