Ubuntu 16.04 GLib-GIO-Message: Using the 'memory' GSettings backend. Your settings will not be saved or shared with other applications
Solution 1:
I get that message when I try to use gsettings directly (seems unrelated to Nvidia driver), and it looks like it is caused by anaconda or miniconda installing their own version of glib. For me, which gsettings shows gsettings within the conda folder tree. If I change my commands from, for example:
gsettings set org.gnome.Evince.Default show-sidebar false
to explicitly calling the system version of gsettings:
/usr/bin/gsettings set org.gnome.Evince.Default show-sidebar false
they don't give that using "memory" backend message, and the setting sticks.