Active Directory Recycle Bin and potential incompatibilities

Having a Windows 2016 based domain (with domain and forest functional level at Windows 2012R2) I would like to enable the recycle bin feature.

However, I understand that this is an one-way change: once enabled, it can not be disabled. So, before doing that, I wonder if there are know incompatibilities and/or integration problems, especially considering that I plan to deploy AD Connect to synchronize our Office365 accounts.

From my understanding, it can be a live-saver especially when using something as AD Connect. Moreover, based on what I read here, the only drawback should be an increase in the DIT file. I am missing something?

I'm not aware of any incompatibilities or integration problems, as you say. I've got many clients with the AD Recycle Bin enabled who are using Azure AD Connect.