What is the difference between `wine` and `wine64`?

Solution 1:

According to winehq.org

• 32 bit Wine runs on both 32-bit and 64-bit Linux/Unix installations. 16-bit and 32-bit Windows applications will run on it.
• 64-bit Wine runs only on 64 bit installations, and so far has only been extensively tested on Linux. It requires the installation of 32 bit libraries in order to run 32 bit Windows applications. Both 32-bit and 64-bit Windows applications (should) work with it;" however, there are still many bugs.

Use the one that works for you.If your applications work with either consider yourself lucky and use either one. There is no right or wrong, just what works for you.

Sources:

• https://wiki.winehq.org/FAQ#Is_there_a_64_bit_Wine.3F
• https://bugs.winehq.org/buglist.cgi?keywords=win64&resolution=---