Office 2008 with Network/Mobile Accounts

At my workplace we use Office without any pain after redirecting the cache (as should be done if network accounts are being used) and ensuring a folder called .TemporaryItems is saved at the root of every share. If that folder does not exist you'll run into issues with Office being unable to save.

Have you been able to see via the crash logs or other logs as to possible reasons for the Office apps to be crashing (beyond a possible corrupted preference file)? The reason I mention a corrupted preference file is that I did have one user's whose copy of Word was unbearably slow and would crash once an hour or so until we deleted the preferences file.