COMODO antivirus installation problem on Ubuntu 16.04LTS

The libssl version on 16.04 is newer than Comodo wants. By the way: ours is newer due to security fixes (...) so the Comodo package you used is too old for 16.04. Comodo got an update on the 31st of August. Make sure you download the latest version as this is more likely to fix the dependency.

If you still get the dependency problem you will need to install an older version manually. You can find the version from precise here. Use dpkg to install this and then install Comodo.

Mind also that the only real use case for anti-virus software is to scan files before you send them to Windows machines. It will not find any virus inside Linux files (since we do not download random software from the web and download software from our repositories and as those are virus free we don't need a virus scanner).

Regarding things in comments:

It will also not prevent phishing nor will it prevent you from problems related to malicious websites. There are other tools for that. For those you have rkhunter, ispprotect (Website malware scanner), chrootkit, lynis and several more. Also be aware that most of those rootkit scanners are also flawed (99.99% of what they claim is a problem is a false positive) and it is best to use 2 or more rootkit scanners and compare results. When 2 or more believe there is a problem you might have one. If only 1 does it is very very likely a false positive.